Climate change is having a devastating impact on human health, with extreme heat contributing to increased illnesses and deaths. The changing weather patterns are also affecting how medications work, making some less effective or even causing adverse reactions. For example, high temperatures can break down certain medicines, while others may not be stable enough for people who live in hot climates. This is particularly concerning for older adults, those with chronic diseases, and people taking specific medications that affect their body's ability to regulate temperature. Furthermore, climate-related disruptions to pharmaceutical supply chains could further limit access to essential medicines, highlighting the urgent need for healthcare systems to prepare for these challenges.