Scientists have discovered a new target for COVID-19 vaccines by identifying a specific area on the virus that can trigger an immune response without neutralizing the virus. The researchers found that antibodies produced by people who have recovered from COVID-19 tend to bind to this "cryptic epitope" when the virus is in its open form, but not when it's closed. This discovery suggests that vaccines targeting this area may be more effective at preventing severe illness and death from COVID-19, even against new variants of the virus.