Breakthrough Discovery on COVID-19's Immune Response

Scientists have discovered a key player in the body's response to COVID-19: an enzyme called Regnase-1. Research found that when this enzyme is not produced, mice are more resistant to a specific strain of the virus and develop less severe pneumonia. The study also showed that neutrophils, a type of white blood cell, play a crucial role in this process. When Regnase-1 is present, it helps regulate the activity of these cells, preventing them from overreacting to the virus. However, when Regnase-1 is absent, the neutrophils become overly active, leading to excessive inflammation and worsening pneumonia. This discovery could lead to new treatments for COVID-19 by targeting this enzyme or modulating its effects on neutrophils.