Indonesia, a country with over 280 million people, has a unique way of understanding the concept of "ikhtiar", which is deeply rooted in its Islamic tradition. This idea may have significant implications for how healthcare professionals approach end-of-life care, making it an important term to understand. Ikhtiar roughly translates to "striving" or "endeavoring", and its meaning goes beyond just physical effort, encompassing a person's spiritual journey and commitment to their faith. As Indonesia is home to the second-largest Muslim population in the world, exploring how ikhtiar can be applied in palliative care settings could provide valuable insights into the country's approach to end-of-life care and add depth to our understanding of medical ethics.